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Irwin Natural Double Potency 5-HTP Extra

Irwin Natural Double Potency 5-HTP Extra

Short Description

Double Potency 5-HTP Extra is a comprehensive formula designed to support mood and relaxation.

Central to this formulation is 5-Hydroxytryptophan (5-HTP), a naturally occurring amino acid that is the immediate precursor of Serotonin.* This plant-derived compound sourced from the Griffonia simplicifolia, a climbing shrub native to West and Central Africa, helps the body to naturally produce this hormone, helping you attain an improved state of well-being.

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To complement the benefits of 5-HTP, this product also features L-Theanine that helps to increase alpha brain waves thereby supporting relaxation of the mind and body. This product also includes other botanicals such as Holy Basil and Damiana that have been used in traditional mood formulas and are known for their adaptogenic properties. This product can be taken daily to help support mood and relaxation, and in doing so, helps promote a more balanced state of mind.

Double-Potency 5-HTP Extra™: Supports Mood and Relaxation

At the center of this formula is 5-Hydroxytryptophan (5-HTP), sourced from the Griffonia simplicifolia, a climbing shrub native to Africa. 5-HTP is the intermediate in the natural conversion of the essential amino-acid tryptophan to serotonin, one of the most important brain neurotransmitters. Serotonin is implicated in the regulation of sleep, mood, and other body functions.[3]

Unlike serotonin, 5-HTP is able to cross the blood-brain barrier to support the body’s natural production of this neurotransmitter. Additionally, taking 5-HTP allows for bypassing the conversion of L-tryptophan into 5-HTP, which is the rate-limiting step in the synthesis of serotonin.


Preliminary research suggests that 5-HTP may help support mood and a more balanced and positive state of well-being.[4]

Double-Potency 5-HTP Extra™: Additional Ingredients

Double-Potency 5-HTP Extra™ also supplies vitamin B6. This vitamin plays a key role in multiple energy-producing pathways in the body and is necessary for proper mental and physical functions. It acts as a coenzyme for many reactions, including the conversion of 5-HTP into serotonin.[3]

In addition to 5-HTP and vitamin B6, Double-Potency 5-HTP Extra™ includes traditional uplifting botanicals like Rhodiola, Damiana, and Saffron, which have been used in mood support formulas for centuries. Plus, it delivers a generous dose of the “sunshine vitamin,” vitamin D3, which plays a vital role in mood regulation.[5]

Double-Potency 5-HTP Extra™: Enhances Relaxation

Because stress is a major antagonist to happiness, this formula also includes relaxing herbs and nutrients to help fight the effects of stress and support relaxation.

Double-Potency 5-HTP Extra™ features L-Theanine, which helps increase alpha brain waves, thereby supporting relaxation of the mind and body.[6]

As a required cofactor for more than 300 enzymatic reactions, magnesium plays an integral role in a wide variety of fundamental cellular activities and metabolic pathways. This mineral is traditionally used and researched to assist with relaxation in the form of releasing muscle tension.[8,9]

This product also contains botanicals such as Holy Basil, Rhodiola, and Damiana that have been traditionally used for their adaptogenic properties. These herbs are known for their ability to support the body’s natural response to physical and emotional stress. In an animal study, holy basil was shown to significantly decrease levels of the “stress hormone” cortisol.[10]

Enhanced Bio-Availability

BioPerine®, a concentrated extract of black pepper, is an important ingredient in all Irwin Naturals® products. Clinically studied in numerous trials, this botanical extract enhances the bioavailability of many of the ingredients in our formulations. When combined with Ginger to create a traditional Ayurvedic blend, the Irwin Naturals® BioPerine® Complex takes bioavailability to the next level.


Double-Potency 5-HTP Extra™ is a comprehensive formula designed to support mood and relaxation. This product includes 5-HTP, plus some of the most revered botanicals to uplift the mind and promote relaxation and calmness. It can be taken daily to help promote a more balanced state of mind.

The nutrients in our Liquid Soft Gel supplements are released fast. Other forms of delivery contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft Gels provide a premium easy-to-swallow delivery system that allows us to combine our nutritious oils such as Flaxseed Oil, and MCT Oil for additional nutritional benefits. But wait! We didn’t stop there. Every Liquid Soft Gel includes our special Bioperine Complex which enhances the bioavailability, absorption and potency of many nutrients.

  • Full Transparency – everything that is in our products is listed on the label. We do not hide anything behind proprietary blends
  • Easy-to-Swallow Liquid Soft Gel Delivery enhanced with Bioperine®

Cura360 Return Policy

Most products featured on can be returned within 30 days of purchase depending upon the manufacturer’s return policy.


For specific return information or authorization, please contact Cura360's Customer Service Department at or call 833-207-3433 for authorization. Returns cannot be processed without contacting Cura360 first, and some items are non-returnable when opened due to health risks.

Generally, you can expect a credit or refund, less a restocking and handling fee, in the same form of payment originally used for your purchase. Credits will be issued within 30 days of the manufacturer receiving your returned product back complete and in good, unused condition in original packaging, and them issuing Cura360 an approval. You will be refunded the purchase price, less the Restocking Fee & applicable shipping fees. You are responsible for the return label and shipping costs. 

·       Restocking Fees range based on the Manufacturers policies, typically between 20-30%

·       All returns MUST be pre-approved by Cura360

·       If a return is not received by the carrier within 15 days after the request has been approved, we will consider the item as not returned and a refund will not be processed

·       Shipping costs are not reimbursable

·       Returns due to damage or defect must be reported as soon as possible and pictures may be required

IMPORTANT If there is significant visible damage to the packaging upon receipt, request that the driver note the damage and request a claim be filed with the carrier for damage. You should also immediately contact Cura360 Customer Service at or call 833-207-3433